The key difference between glycolic acid and hyaluronic acid is that the glycolic acid is the simplest alpha hydroxy acid whereas hyaluronic acid is the only non-sulfated glycosaminoglycan. Furthermore, glycolic acid naturally occurs in some sugar-crops while hyaluronic acid naturally occurs in the human body.
Both glycolic acid and hyaluronic acid are common ingredients in various skincare products. This is because these compounds can improve the overall look of the skin. Apart from that, there are many applications of these compounds as stated below.